Human Infection with Ehrlichia muris–like Pathogen, United States, 2007–20131

نویسندگان

  • Diep K. Hoang Johnson
  • Elizabeth K. Schiffman
  • Jeffrey P. Davis
  • David F. Neitzel
  • Lynne M. Sloan
  • William L. Nicholson
  • Thomas R. Fritsche
  • Christopher R. Steward
  • Julie A. Ray
  • Tracy K. Miller
  • Michelle A. Feist
  • Timothy S. Uphoff
  • Joni J. Franson
  • Amy L. Livermore
  • Alecia K. Deedon
  • Elitza S. Theel
  • Bobbi S. Pritt
چکیده

An Ehrlichia muris-like (EML) pathogen was detected among 4 patients in Minnesota and Wisconsin during 2009. We characterized additional cases clinically and epidemiologically. During 2004-2013, blood samples from 75,077 patients from all 50 United States were tested by PCR from the groEL gene for Ehrlichia spp. and Anaplasma phagocytophilum. During 2007-2013, samples from 69 (0.1%) patients were positive for the EML pathogen; patients were from 5 states: Indiana (1), Michigan (1), Minnesota (33), North Dakota (3), and Wisconsin (31). Most (64%) patients were male; median age was 63 (range 15-94) years; and all 69 patients reported likely tick exposure in Minnesota or Wisconsin. Fever, malaise, thrombocytopenia, and lymphopenia were the most common symptoms. Sixteen (23%) patients were hospitalized (median 4 days); all recovered, and 96% received doxycycline. Infection with the EML pathogen should be considered for persons reporting tick exposure in Minnesota or Wisconsin.

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عنوان ژورنال:

دوره 21  شماره 

صفحات  -

تاریخ انتشار 2015